Publication

Disambiguation of similar object-place paired associations and the roles of the brain structures in the medial temporal lobe.
Author
Byun, J. and Lee, I.
Year of publication
2010
Title of paper
Disambiguation of similar object-place paired associations and the roles of the brain structures in the medial temporal lobe.
Publication in journal
Experimental Neurobiology
Vol
19
File
en-19-15.pdf (211.8K) 40회 다운로드 DATE : 2021-11-04 13:37:59
Amnesic patients who have damage in the hippocampus and in associated areas in the medial temporal lobe suffer from remembering specific events that may or may not share similar objects and locations. Computational models, behavioral studies, and physiological findings all suggest that neural circuits in the hippocampus are suitable for representing seemingly similar events as distinctively different individual event memories. This article offers a selective review on this particular function of the hippocampus and its associates areas such as the perirhinal cortex, mostly centering upon lesion studies and physiological studies using animals. We also present recent experimental results showing that the dentate gyrus subfield of the hippocampus and perirhinal cortex are particularly important for discriminating similar paired associates between same objects and different locations, or vice versa.